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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '357ed5754a6a2af78e44deb38a910bcf6aa1ccbe7bc4bdeb83ad60b3f2e9957f' 
  AND token = 'nIre6sBxoXkDl7FOIxnBUOuSpwLi2WmDpHHnGBPiBm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}