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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a53856ed92d61dc0f6f061a76bdfaf7484deb4f94a7b94e79efc2c0ba59bc59' 
  AND token = 'iaXVBL0JWR1+V0oW/d8L5647ObQZewHEELG+cMQLDf4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}