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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bd0f0367d7035953c86dd40dc746851f1a450833a188acbd2b962f7b57bf5e3' 
  AND token = '+WuirDSnqD9DWs07mErkfiWPdZgHhWNRqz9yQV2JgEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}