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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b8611ac8ea0b65de66ddddd0c011372a5a455aadb8f31d250f9a15d03f4cd81' 
  AND token = 'YnyVRzE+e0eIuDPD4b+a870OKT/7gnSyLSmhRkzks3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}