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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f82262f0d5c952fc2b95e59904adb63389f1eb9b07459206d437c8c62368900' 
  AND token = 'NpO9jgCyBUF7nDcZq16lbx+JpxYxXIMq7OJLR2b+Zq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}