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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1d3b450d3c8a71edf4cbf45685b264f47ee59b35e20b2f4b096013d4b816ed3' 
  AND token = 'Tgzi1xv99oYalTeHAhnmHhCXVnui8f4XlYtbGnJ1VG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}