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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4a63bbbbc65ac332ba5bbbedde8a5291d0c01ab056bbb50ccb106c836addf50' 
  AND token = 'KbV7qJncHkg/NkSMPTUj/LiJfuVRRlA6c93R52dTsZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}