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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a1276f7913e74920974d7f2e0bb8695f99634fc446b560d5d741486a696820f' 
  AND token = 'FB718+ewv4SQBsPtAJQeyDZYRHjYca2HbB2xmVMw5bw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}