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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1eb6b5af886d581d4080c958b9f2e004d17fff9c691cb4a5b9b7a4cd0f5103a8' 
  AND token = '+HhACXbtr5dWPPelUwadyyT2V7MDOHPDbuT5CYAhIQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}