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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd486b8dff30d3ab4bd9a2f745155a3c24dc2ab4ead1bca0ab05398dce48b4145' 
  AND token = 'SFKHaabHK+8fD+JGIBhouVm2F368kh/yaq1FHty9On8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}