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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6689bed3a6c24adaed676ae4e186ad7eca27aaeb7e2296b9fc96cd34897de379' 
  AND token = '4o1V9rpNKllDB1nmwT2KO2JE6Pbb3moxz9BCeXKt8ZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}