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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5e7c0c431b80603c447cfb0b8b0fcdcfd944e24a0bbe19c1fc1a244fa177125' 
  AND token = 'SuaG7SoBVaIBZamOn+4GvGD3A3L3unp2qn5QtZdRCjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}