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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccef0496e71f197e488ff65d3abe3c1605d521382b4fc53ccaa5f2926f6f29f1' 
  AND token = 'cxMkOXYq/VnaH5eV9DWBJBm+n7LpFlmLwIYHYy50p88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}