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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1f4157e69abebf81f1bef376fde854bb76027414e01c074518b6fd8e790def1' 
  AND token = 'ZMt9kVN/963C9xB8Vmj9qYZKV0eCwetcX1qdEiT6tTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}