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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7323296608a659a53cdf56db85cadef34c1817fc3a0f7b24eaeaa1d42fbe2af8' 
  AND token = 'v5jj+PK1s7p1OGEnIEUlL5xUWUB+NerKN5BUBF/59+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}