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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b8dbe3ca577ad078a0c90dbbf7965a5d83129e1cbbf7617320bb7a05f1b2071' 
  AND token = 'Of0K51Ktjkf5Hr3WkicPHuJjUxcBno/qq1dunr0p8r0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}