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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2eee5278373428b2f3ded6381e5bf8825fdc9ba7b0410050f0e18fa595b9e6d0' 
  AND token = 'grDRHLewnS0Fl5oHG1Uk5Z5IxSjn5uuBZvAjsk9TbK8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}