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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c46c718a5e4f4312cae1cd13dcc9e455efcb6295331ec992db1b7c7230bfab6' 
  AND token = 'vA+2uqe6UDObaTUb9QvNS7kfXA4w2BT8C6ucwH8U3sE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}