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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bb0b1d63e89ec4194db003d1c0417f3468d096aba9d8483c2944a585c49bff8' 
  AND token = 'ZnHmdW+Ke+R1oyYoEM49XPDJrecOznEOipqAUF0OzsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}