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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd472cdd3da4f672dbe11367c9f991daa3e2eb48a59fce156a70ae3fe556b443' 
  AND token = 'oS2bNAF0JFP3PWKKYUKNB0gLAFTFYHIy6rHDSL4xZAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}