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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8db5aeb4fffb74c2a3cce9ec2c355e0647a95ff965d7be447a662d5a4330086d' 
  AND token = 'yXSlmbbiaq1riAlBne03l5Z2Sf7y8nQMJNRPjIko8Sg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}