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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e1007251db33587f5628916e4d49cef8378532800c7265fb5898f9753ecca9d' 
  AND token = 'M8/C5cq7x4tT3SI1zUgRnLqpmZgQc9NQRtvbC+MXZG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}