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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f81a628056f8a6310cca0a8d0b42bf4aeedccb1fe0eff0007d9ec3480b86b896' 
  AND token = 'T5RyFUy7DF5xS+xJ1SjJrNvyqiLTOIcQuUlNUTc1Ey0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}