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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd12165aaf61dac37f7b00844a4ba12cdfa69e43c9ca7a0640e4e29cb7118274' 
  AND token = 'w/0tg+RA56oSwaDIpSSgxa3EsG5+Ugkw+MFKYjXGkEE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}