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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '239bde7a1293d5dfdeae8528e0683285d00ee0aac028d1b9c69b4635fc0e1b86' 
  AND token = 'sfEMpfBryDFdK9iDfmzyua6JujFh2emT4952FZ81Dro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}