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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e8e031c4bde2678979b72d024caa99bb254fd1ed623366448f82fedf14a4a3a' 
  AND token = 'PrtmzmlGQzKd6DWsl902HDs/HdYlkuaHRQl0v9zWGMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}