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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34884865e7408f9bdc728cf51d45500766bbfe0a0fbf93e845224801e3253493' 
  AND token = 'DypiajbBbDhJl2LHc3I314C57+ipkTsvltRB0irnRds=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}