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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '881028cbb61e0a8baf16c2144306880efc38c65b44c387356c141e04b2b89f18' 
  AND token = 'sxXsD5YPDRLIIWm8AclNpxMcjJfYaBsuMo8Xeu1mmn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}