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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8748ffc59e1608d8d336080223c393f1890e7f58f3e3255159b7a0b6fe95c80' 
  AND token = 'emqnpXONaGoEIlnkQM6HmvjdRw0lpTM25NrPQdxgcJU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}