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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e15678274c4b78d4587e4eeb1b8bbdbcb29db21b46a4d742f43635ce48b5bb9' 
  AND token = 'R/wYgdqYq6FFY7OaroJMaAWgb16FwIihbehgLHZjPMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}