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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bfee375bab048871ae632ed2455cd37c20a0fb82fd231065b1dbd8e5917f771' 
  AND token = 'pbZmq/x4ECTNqGOrmSP02xBDtBLH3oWSUuqa+K8Mu3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}