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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a1c71cdd1098b3431b063228ff2ad21a460c455d2e0ff0174f0b6ab2ed6c32d' 
  AND token = 'VqzZ6L4LH0K6eZ6Fn0vf734N2qJJy29UKdmdQ2hXtR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}