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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '199f682bfd8549503c0c97dbd1eb459702850f34251300d5b77b93323cfea1fc' 
  AND token = 'GfaURsM+OBPtw2MDGHEkprZh3wZAF/psmdykdj9RlX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}