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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b57f4fdd8517e5bd33d06aaa04695b9a590a884f9db7650ff40e43fddc3bbc6e' 
  AND token = 'v7X6vS6nWfQg1+eU6WAVPjW+7k0mA1hUGPacqmFWA2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}