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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6773a11d3f1774cc5b891024b13f35013e04e1270ea72cce65f52402524ef3e3' 
  AND token = 'e1W08MDUIUssIgfdz6JDmQGSsQMXf7I88BAq0FhlR94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}