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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f7a11f857d3beaf19762a7e0534e233570df2f9b7091a5bc6f1ae4599615cc' 
  AND token = 'QPpvNUuHtLLq3pTh96v0VIw+LioNH40h5sC8Jhr4P7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}