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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74f69aa668235b75727cbc63bc4ddd96f348b5be982a73606390b7667873607b' 
  AND token = 'R2jeMyDMwfJC1ybtrORkw1fh0R2PuW2TlZE4jTZu6SU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}