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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43dd18b63e209c0a6bf1d7b55b2238b694b5fbffbe07926670105250a5cf3376' 
  AND token = 'nk79sw2LBeO6oAlyi6Rxqq24DjRhuiQWdKZBX1evo2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}