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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fa5aaa0a7cb99a30cbd09aa69fa758686ed66e32fc972b5629882b023526ad6' 
  AND token = '0dKH9jmJoNDqhVJL2d1JKSQ6QJL9mykhvyhwN3elOXc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}