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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '799aa6d83f922f6947af2d38653b12fb8d4d44e150e303b82264cc34e2c22441' 
  AND token = 'S3JNOmnvTfwgmgTDaZXJ+1snER9P/v+dA3yjv3pGJUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}