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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69edb23cb509467116f335c9a5a07a37ebc0d50ab2cbdd031d1f03d043cd2f90' 
  AND token = 'uQzTFZ+QRY+PTmpynueD5V/KUKK9XyW4XJpeu9BiH8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00107

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}