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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cde61192da5875aab93c8ceae23f27cf4d0ba1de1327e3f887e15c6b0591b151' 
  AND token = '+ZW2kUn7GzYq1HxOn+0WdRfd8mQmPCPwYe1BEn/Ya8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}