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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72f24587263d3bc81b2a93a635dc410f7ec3c3d1d2ec5e184fb5d7d8c2da6ceb' 
  AND token = 'IAQwOCmcIVTCGOALH2LZf4ZuvDiIqgkqEufjHc5Lzso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}