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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7de4f4a685f44ecbb4f776b27425fe46163392258e34c33ed407440cade1e6ac' 
  AND token = 'fnd3MFTCwqYDYCA0wiLtePD2PzCE4uos/E7Cy6H751Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}