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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd58b9f4ba91ecdc16f7061b8417489a9c1ad9225e4163925f89b305a1aafe136' 
  AND token = 'X2r2vpflIVM4TSMSFEpx1db+ALI2CuP2IuzaIfVe5+U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}