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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb503eaf81774f1d43d817f10bfb64898db5e7a650f50f304847e6003f4c3869' 
  AND token = 'vRt6kCQQxO1okXzt8LWuwObmuddUZq9UxhNm+rX/FRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}