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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe1d22bd4ab4bb3283469fc18547024de52da320a2a015bbaf3010d6c1438f37' 
  AND token = 'zjyGEkSg0C9uNOaIAUH35VBxAh0IjprOOLd3fZX+toA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}