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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50f98fa9a3f85ab14683e391f76a22410a9f654b207e62a4a83f1c02cf492532' 
  AND token = 'gRYgWU8J4/xbLXZrA1p0n8t6GfgtRSp+UHI6TpHuss4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}