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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c238e4b3202aace63acdbce1a66d27512e869cab20151a6e27353d6aa509d1f' 
  AND token = 'HQl0wW8iPfe7DyYOAbeOB8p2dJJACFUvxTGC2ryWh/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}