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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd91bfe94e520e6c015b8754e32b740503412ffb2e0732f149f71a718435f05a2' 
  AND token = 'dhLk2/irh791xohgoi42tDuDZhSKaxfeXbHO57eKeuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}